Mathematical Disease Progression Modeling in Type 2/3 Spinal Muscular Atrophy

Jacqmin P, Gieschke R, Delor I, Snoeck E, Vianna E, Vuillerot C, Sanwald Ducray P.
Muscle Nerve. 2018. 58(4):528-535.
Presentation of a mathematical model that empirically describes the development and deterioration of muscle function assessed by the 3 domains of MFM in Spinal Muscular Atrophy (SMA).

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Keywords : Disease progression, Drug development, Mathematical modeling, MFM, Spinal Muscular Atrophy

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