Monitoring changes and predicting loss of ambulation in Duchenne muscular dystrophy with the Motor Function Measure
Vuillerot C, Girardot F, Payan C, Fermanian J, Iwaz J, de Lattre C, Bérard C.
Dev med Child Neurol 2009. 52(1): 60-65.
Changes in MFM scores of 12 DMD patients treated with corticosteroids and 54 without treatment. The results support the use of MFM in the treatment of patients with Duchenne muscular dystrophy and its use in clinical trials to evaluate patients receiving a therapy. The MFM also help to predict the loss of walk for patients with DMD.
Keywords: Duchenne Muscular Dystrophy, MFM, Corticosteroids, Loss of walk, Management of patients
Articles dans les revues scientifiques
Nitric oxide donor and non steroidal anti inflammatory drugs as a therapy for muscular dystrophies: evidence from a safety study with pilot efficacy measures in adult dystrophic patients.
D'Angelo MG, Gandossini S, Martinelli Boneschi F, Sciorati C, Bonato S, Brighina E, Comi GP, Turconi AC, Magri F, Stefanoni G, Brunelli S, Bresolin N, Cattaneo D, Clementi E. Pharmacol Res. 2012. 65(4): 472-9. The main of this monocentric pilot study was to evaluate...
Gait Assessment in Children With Duchenne Muscular Dystrophy During Long-Distance Walking
Ganea R, Jeannet PY, Paraschiv-Ionescu A, Goemans N, Piot C, Van den Hauwe M, Aminian K. J Child Neurol. 2012. 27: 1 30-38. Gait patterns of 25 children with Duchenne muscular dystrophy were compared to that of healthy children. Authors showed that Duchenne muscular...
Motor function measure scale, steroid therapy and patients with Duchenne muscular dystrophy.
Silva EC, Machado DL, Resende MB, Silva RF, Zanoteli E, Reed UC. Arq Neuropsiquiatr. 2012. 70(3): 191-5. Description of the evolution of the motor function of 33 DMD patients (27 ambulant and 6 non ambulant at inclusion) treated with steroids during 18 month assessed...
Quantitative MRI can detect subclinical disease progression in muscular dystrophy.
Fischmann A, Hafner P, Fasler S, Gloor M, Bieri O, Studler U, Fischer D. J Neurol. 2012. 259(8): 1648-54. The aim of this study was to compare different methods of quantitative and semiquantitative MRI in order to validate clinical parameters for the follow-u of...
The assisted 6-minute cycling test to assess endurance in children with a neuromuscular disorder.
Jansen M, De Jong M, Coes HM, Eggermont F, Van Alfen N, De Groot IJ. Muscle Nerve. 2012. 46(4): 520-3. Development of the "assisted 6-minute cycling" aiming to assess DMD patients' endurance.MFM is use as a gold standard.PubMed linkKeywords: Assisted 6-minute cycling...
Muscular involvement assessed by MRI correlates to motor function measurement values in oculopharyngeal muscular dystrophy
Fischmann A, Gloor M, Fasler S, Haas T, Rodoni Wetzel R, Bieri O, Wetzel S, Heinimann K, Scheffler K, Fischer D. J Neurol 2011. 258: 1333–1340. Oculopharyngeal muscular dystrophy (OPMD) is a progressive skeletal muscle dystrophy characterized by ptosis, dysphagia, and...