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Création et validation d’une classification en grade de sévérité dans les maladies neuromusculaires : la classification NM-Score

Vuillerot C, Rippert P, Roche S, Bérard C, Margirier F, de Lattre C, Poirot I, Berruyer A, Tiffreau V, Fournier-Mehouas M, Bouhour F, Urtizberea JA, Renders A, Ecochard R; Le groupe d’étude NM-Score.
Ann Phys Rehabil Med. 2013. 56(9-10):673-86.
Development of a classification for neuromuscular disease patients in each of the three motor function domains (D1: standing and transfers; D2: axial and proximal function; D3: distal function). Several qualitative validation studies (according to the Delphi method) and quantitative validation studies (content validity, criterion validity and inter-rater reliability) were used. The inter-rater agreement was good when the classification was based on patient observation or an interview with the patient. Stronger correlations (according to Spearman’s coefficient) with the respective ‘‘gold standard’’ classifications were found for NM-Score D1 (0.86 vs. the Vignos Scale and [1]0.88 vs. MFM]-D1 and NM-Score D2 ([1]0.7 vs. the Brooke Scale and 0.64 vs. MFM-D2) than for NM-Score D3 (0.49 vs. the Brooke scale and [1]0.49 vs. MFM-D3). The NM-Score is a reliable, reproducible outcome measure with value in clinical practice and in clinical research for the description of patients and the constitution of uniform patient groups (in terms of motor function).

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Keywords: Activities of daily living, Motor function, Neuromuscular disease, Outcome measure

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