The 6-minute walk test, motor function measure and quantitative thigh muscle MRI in Becker muscular dystrophy: A cross-sectional study

Fischer D, Hafner P, Rubino D, Schmid M, Neuhaus C, Jung H, Bieri O, Haas T, Gloor M, Fischmann A, Bonati U.
Neuromuscul Disord. 2016. 26(7):414-22.
This study investigated the relation between validated functional scores, such as MFM, timed function tests, such as the 6-minute walk test (6MWT), and quantitative MRI (qMRI) of thigh muscles in 20 ambulatory Becker muscular dystrophy (BMD) patients.
Mean fat fraction (MFF) and global transverse relaxation time (T2) times were highly negatively correlated with the MFM total, D1-subscore and 6MWT.

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Keywords: Becker muscular dystrophy; Dystrophinopathy; Imaging biomarker; Quantitative MR; Timed function tests

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