Longitudinal Functional and NMR Assessment of Upper Limbs in Duchenne Muscular Dystrophy
Neurology. 2016. 15;86(11):1022-30.
Twenty-five 53-skippable patients with DMD were included in this study. Patients underwent clinical and functional assessments every 6 months using the Motor Function Measure (MFM), hand grip and key pinch strength, MoviPlate, and NMR spectroscopy.
Overall, NMR alterations observed in the upper limb of patients correlated with those observed in the lower limbs of younger patients. Fat infiltration correlated with clinical assessments such as MFM.
Articles in scientific journals
Facioscapulohumeral dystrophy in children: design of a prospective, observational study on natural history, predictors and clinical impact (iFocus FSHD)
Goselink RJ, Schreuder TH, Mul K, Voermans NC, Pelsma M, de Groot IJ, van Alfen N, Franck B, Theelen T, Lemmers RJ, Mah JK, van der Maarel SM, van Engelen BG, Erasmus CE. BMC Neurol. 2016. 17;16:138. Protocol of a population-based prospective cohort study on...
Muscle MRI Findings in Childhood/Adult Onset Pompe Disease Correlate with Muscle Function
Figueroa-Bonaparte S, Segovia S, Llauger J, Belmonte I, Pedrosa I, Alejaldre A, Mayos M, Suárez-Cuartín G, Gallardo E, Illa I, Díaz-Manera J; Spanish Pompe Study Group. PLoS One. 2016. 6;11(10):e0163493. The main objective of the study was to assess the use of muscle...
The 6-minute walk test, motor function measure and quantitative thigh muscle MRI in Becker muscular dystrophy: A cross-sectional study
Fischer D, Hafner P, Rubino D, Schmid M, Neuhaus C, Jung H, Bieri O, Haas T, Gloor M, Fischmann A, Bonati U. Neuromuscul Disord. 2016. 26(7):414-22. This study investigated the relation between validated functional scores, such as MFM, timed function tests, such as...
Therapy Taping Method: Therapeutic approach in two children with Duchenne Muscular Dystrophy
Iwabe-Marchese C, Morini NJr. Br J Med Med Res. 2016. 15(3): 1-7. The aim of the study is to assess the effect of elastic bandage through the Therapy Taping Method in two children with DMD. The Motor Function Measure-20 scale (MFM-20) was used as an outcome...
Natural history of LGMD2A for delineating outcome measures in clinical trials
Richard I, Hogrel JY, Stockholm D, Payan CA, Fougerousse F; Calpainopathy Study Group, Eymard B, Mignard C, Lopez de Munain A, Fardeau M, Urtizberea JA. Ann Clin Transl Neurol. 2016. 4;3(4):248-65. Observational study of clinical manifestations and disease progression...
Broadening The Imaging Phenotype of Dysferlinopathy at Different Disease Stages
Díaz J, Woudt L, Suazo L, Garrido C, Caviedes P, Cardenas AM, Castiglioni C, Bevilacqua JA. Muscle Nerve. 2016. 54(2):203-10. The study aimed at describes MRI of dysferlinopathy and to correlate it with objective measures of motor dysfunction.MRI infiltration score...