Longitudinal Functional and NMR Assessment of Upper Limbs in Duchenne Muscular Dystrophy

Hogrel JY, Wary C, Moraux A, Azzabou N, Decostre V, Ollivier G, Canal A, Lilien C, Ledoux I, Annoussamy M, Reguiba N, Gidaro T, Le Moing AG, Cardas R, Voit T, Carlier PG, Servais L.
Neurology. 2016. 15;86(11):1022-30.
Twenty-five 53-skippable patients with DMD were included in this study. Patients underwent clinical and functional assessments every 6 months using the Motor Function Measure (MFM), hand grip and key pinch strength, MoviPlate, and NMR spectroscopy.
Overall, NMR alterations observed in the upper limb of patients correlated with those observed in the lower limbs of younger patients. Fat infiltration correlated with clinical assessments such as MFM.

PubMed  link

Articles in scientific journals

Short-TERM Neuromuscular Electrical Stimulation Training of the Tibialis Anterior Did Not Improve Strength and Motor Function in Facioscapulohumeral Muscular Dystrophy Patients

Doix AM, Roeleveld K, Garcia J, Lahaut P, Tanant V, Fournier-Mehouas M, Desnuelle C, Colson SS, Sacconi S Am J Phys Med Rehabil. 2017. 96(4):e56-e63. Prospective study including 10 patients with facioscapulohumeral muscular dystrophy type 1 (FSHD1) and 10 healthy...

read more