Hammersmith Functional Motor Scale and Motor Function Measure-20 in non ambulant SMA patients
E. Mazzone, R. De Sanctis, L. Fanelli, F. Bianco, M. Main, M. van den Hauwe, M. Ash, R. de Vries, J. Fagoaga Mata, K. Schaefer, A. D’Amico, G. Colia, C. Palermo, M. Scoto, A. Mayhew, M. Eagle, L. Servais, M. Vigo, A. Febrer, R. Korinthenberg, M. Jeukens M. de Viesser, A. Totoescu, T. Voit, K. Bushby, F. Muntoni, N. Goemans, E. Bertini, M. Pane, E. Mercuri.
Neuromuscul Disord. 2014. 24:347-352.
Evaluation of the correlation between the Hammersmith Functional Motor Scale and the MFM-20 in non-ambulant SMA children and adults at baseline, and over a 12 months period. Seventy-four patients performed both measures at baseline and 49 also had an assessment 12 months later. The correlation between the two scales was 0.733. The 12 month changes ranged between [1]11 and 4 for the Hammersmith and between [1]11 and 7 for the MFM-20. The results suggest that both scales provide useful information although they appeared to work differently at the two extremes of the spectrum of abilities. Hammersmith appeared to be more suitable in strong non ambulant patients, while the MFM-20 appeared to be more sensitive in the very weak patients.
Keywords: Outcome measures, Spinal muscular atrophy
Articles dans les revues scientifiques
Functional outcome measures for infantile Charcot-Marie-Tooth disease: a systematic review
Mandarakas MR, Rose KJ, Sanmaneechai O, Menezes MP, Refshauge KM, Burns JJ Peripher Nerv Syst. 2018. 23(2), 99-107. Systematic review of the outcome measures that can be used in children with Charcot-Marie-Tooth (CMT) aged 0 to 3 years.Properties of MFM-20 in this...
Timed function tests, motor function measure, and quantitative thigh muscle MRI in ambulant children with Duchenne muscular dystrophy: A cross-sectional analysis
Schmidt S, Hafner P, Klein A, Rubino-Nacht D, Gocheva V, Schroeder J, Naduvilekoot Devasia A, Zuesli S, Bernert G, Laugel V, Bloetzer C, Steinlin M, Capone A, Gloor M, Tobler P, Haas T, Bieri O, Zumbrunn T, Fischer D, Bonati U Neuromuscul Disord. 2018....
Corticosteroids in Duchenne muscular dystrophy: impact on the motor function measure sensitivity to change and implications for clinical trials
Schreiber A, Brochard S, Rippert P, Fontaine-Carbonnel S, Payan C, Poirot I, Hamroun D, Vuillerot C Dev Med Child Neurol. 2018. 60(2):185-191. The aim of the study was to monitor the evolution of the motor function of ambulatory patients with Duchenne muscular...
Quantitative muscle MRI to follow up late onset Pompe patients: a prospective study
Figueroa-Bonaparte S, Llauger J, Segovia S, Belmonte I, Pedrosa I, Montiel E, Montesinos P, Sánchez-González J, Alonso-Jiménez A, Gallardo E, Illa I, Díaz-Manera J ; Spanish Pompe group.Sci Rep. 2018. 18;8(1):10898. In this study, 32 Late onset Pompe disease patients...
Turkish version of the Motor Function Measure Scale (MFM-32) forneuromuscular diseases: a cross-cultural adaptation, reliability, and validity study
Inal HS, Tarakçi E, Tarakçi D, Aksoy G, Mergen Kiliç S, Beser H, Beser Ç, Özdinçler AR, Durmus Tekçe H, Parman FY, Deymeer F, Oflazer ZP Turk J Med Sci. 2017. 19;47(6):1826-1833. Study aiming to analyze the reliability and validity of a translation and cultural...
Long term longitudinal study of muscle function in patients with glycogen storage disease type IIIa
Decostre V, Laforêt P, De Antonio M, Kachetel K, Canal A, Ollivier G, Nadaj-Pakleza A, Petit FM, Wahbi K, Fayssoil A, Eymard B, Behin A, Labrune P, Hogrel JY Mol Genet Metab. 2017. 122(3):108-116. Preliminary results of a longitudinal study assessing in patients with...