Hyperleptinemia in children with autosomal recessive spinal muscular atrophy type I-III

Kölbel H, Hauffa BP, Wudy SA, Bouikidis A, Della Marina A, Schara U 
PLoS One. 2017. 9;12(3):e0173144.
 
Study of prevalence of hyperleptinemia in a spinal muscular atrophy (SMA) population.
Hyperleptinemia is highly prevalent in underweight children with SMA and is associated with disease severity and decreased motor function as assessed by MFM-32.

PubMed link

Keywords: Hyperleptinemia ; spinal muscular atrophy

Articles in scientific journals

Protocol for a phase II, monocentre, double-blind, placebo-controlled, cross-over trial to assess efficacy of pyridostigmine in patients with spinal muscular atrophy types 2-4 (SPACE trial)

Stam M, Wadman RI, Wijngaarde CA, Bartels B, Asselman FL, Otto LAM, Goedee HS, Habets LE, de Groot JF, Schoenmakers MAGC, Cuppen I, van den Berg LH, van der Pol WL. BMJ Open. 2018. 30;8(7):e019932.  Protocol of the "SPACE" in wich MFM is used as an outcome measure....

read more