Timed function tests, motor function measure, and quantitative thigh muscle MRI in ambulant children with Duchenne muscular dystrophy: A cross-sectional analysis

Schmidt S, Hafner P, Klein A, Rubino-Nacht D, Gocheva V, Schroeder J, Naduvilekoot Devasia A, Zuesli S, Bernert G, Laugel V, Bloetzer C, Steinlin M, Capone A, Gloor M, Tobler P, Haas T, Bieri O, Zumbrunn T, Fischer D, Bonati U 
Neuromuscul Disord. 2018. 28(1):16-23.
Cross-sectional study in ambulatory patients with Duchenne Muscular Dystrophy assessing the relationship between validated clinical evaluations, such as the 6-minute walk test and MFM, and quantitative muscle MRI of the thigh muscles.
All clinical evaluations were strongly correlated, with p <0.001. The highest correlation was found between MFM score D1 and the 6-minute walk test.

PubMed link

Keywords: 6-minute walk test, Duchenne Muscular Dystrophy, Imaging Biomarkers, MFM, Quantitative MRI

Articles dans les revues scientifiques