Adding quantitative muscle MRI to the FSHD clinical trial toolbox
Mul K, Vincenten SCC, Voermans NC, Lemmers RJLF, van der Vliet PJ, van der Maarel SM, Padberg GW, Horlings CGC, van Engelen BGM
Neurology. 2017. 14;89(20):2057-2065.
Assessment from a cohort of 140 patients with facioscapulohumeral muscular dystrophy (FSHD) of correlation between quantitative MRI and MFM, FSHD clinical score, Ricci score, and 6-minute walking test.
The mean fat fraction of the total leg musculature correlated highly with the MFM (correlation coefficient of -0.845).
Keywords : Facioscapulohumeral muscular dystrophy, quantitative MRI
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