Assessment of respiratory muscles and motor function in children with SMA treated by nusinersen
Respiratory muscles performance and lung function were evaluated in children with SMA 1 and 2 after six injections of nusinersen (M14). Treated subjects were assessed with MFM and HINE-2 at baseline and M14.
A significant improvement in MFM and HINE-2 was observed at M14 as compared with baseline.
Keywords: lung function; motor function; nusinersen; respiratory muscles; spinal muscular atrophy.
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