Monitoring changes and predicting loss of ambulation in Duchenne muscular dystrophy with the Motor Function Measure
Vuillerot C, Girardot F, Payan C, Fermanian J, Iwaz J, de Lattre C, Bérard C.
Dev med Child Neurol 2009. 52(1): 60-65.
Changes in MFM scores of 12 DMD patients treated with corticosteroids and 54 without treatment. The results support the use of MFM in the treatment of patients with Duchenne muscular dystrophy and its use in clinical trials to evaluate patients receiving a therapy. The MFM also help to predict the loss of walk for patients with DMD.
Keywords: Duchenne Muscular Dystrophy, MFM, Corticosteroids, Loss of walk, Management of patients
Articles dans les revues scientifiques
Molecular therapeutic strategies for spinal muscular atrophies: current and future clinical trials
Zanetta C, Nizzardo M, Simone C, Monguzzi E, Bresolin N, Comi GP, Corti S. Clin Ther. 2014. 1;36(1):128-40. This article provides a general overview of the main aspects that need to be taken into account to design a more efficient clinical trial and to summarize the...
Relationship between muscle strength and motor function in Duchenne muscular dystrophy
Nunes MF, Hukuda ME, Favero FM, Oliveira AB, Voos MC, Caromano FA. Arq Neuropsiquiatr. 2016. 74(7):530-5. This study investigates the relationship between muscle strength as measured by Medical Research Council (MRC) scale and MFM and between these variables and age...
Influence of a two-year steroid treatment on body composition as measured by Dual X-Ray Absorptiometry in boys with Duchenne Muscular Dystrophy
Vuillerot C, Braillon P, Fontaine-Carbonnel S, Rippert P, André E, Iwaz J, Poirot I, Bérard C. Neuromuscul Disord. 2014. 24:467-473. Assessment of effects of long term steroid treatments on body composition, assessed by Dual X-Ray absorptiometry, in 21 patients with...
The applicability of four clinical methods to evaluate arm and hand function in all stages of spinal muscular atrophy type II.
Werlauff U, Fynbo Steffensen B. Disabil Rehabil. 2014. 36(25):2120-6. Assessment of ability of 4 clinical methods to reflect arm and hand function at impairment and activity level and to determine their ability to discriminate among SMA II patients of all ages and in...
Diaphragmatic dysfunction in Collagen VI myopathies
Quijano-Roy S, Khirani S, Colella M, Ramirez A, Aloui S, Wehbi S, de Becdelievre A, Carlier RY, Allamand V, Richard P, Azzi V, Estournet B, Fauroux B. Neuromuscul Disord. 2014. 24(2):125-33. A pilot study aimed at characterizing the respiratory muscle phenotype in...
Hammersmith Functional Motor Scale and Motor Function Measure-20 in non ambulant SMA patients
E. Mazzone, R. De Sanctis, L. Fanelli, F. Bianco, M. Main, M. van den Hauwe, M. Ash, R. de Vries, J. Fagoaga Mata, K. Schaefer, A. D’Amico, G. Colia, C. Palermo, M. Scoto, A. Mayhew, M. Eagle, L. Servais, M. Vigo, A. Febrer, R. Korinthenberg, M. Jeukens M. de Viesser,...