The motor function measure to study limitation of activity in children and adults with Charcot-Marie-Tooth disease
Allard L, Rode G, Jacquin-Courtois S, Pouget MC, Rippert P, Hamroun D, Poirot I, Bérard C, Vuillerot C; le groupe d’étude CMT MFM.
Ann Phys Rehabil Med. 2014. 57(9-10):587-99.
Study on 233 Charcot-Marie-Tooth disease patients aged 4–86 years aiming at studying the applicability and responsiveness of the MFM (total score and sub-scores D1, D2 and D3).
MFM decrease with age, especially sub-scores D1 and D3. There were no significant differences between the scores according to type of Charcot-Marie-Tooth disease. Concerning the responsiveness, a significant responsiveness was demonstrated only in type 2 Charcot-Marie-Tooth disease.
Results suggest that, especially for D1 and D3 sub-scores, the MFM is a reliable and valid outcome measure that can be usefully applied in longitudinal follow-up.
Keywords: Charcot-Marie-Tooth disease, Motor Function Measure, Activity limitation, Neuromuscular disease, Functional scale
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