Diagnostic et histoire naturelle de la dystrophie musculaire de Duchenne

Desguerre I, Laugel V.
Arch Pediatr. 2015. 22(12 Suppl 1):12S24-30.
Duchenne myopathy is today the most frequently encountered progressive muscular dystrophy in children, with an inexorable, progressive development to death in the third decade. Improvement in survival is related to improvement in orthopaedic management, early screening of cardiac and respiratory complications, but no curative therapy can be applied today beyond recent pharmacogenetic advances.
Identification of outcome measures such as the 6-minute walk test, the MFM score, manual muscle testing musculaire, or biomarkers is indispensable for patient follow-up and collaborative studies.

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