Functional assessment tools in children with Pompe disease: A pilot comparative study to identify suitable outcome measures for the standard of care
Ricci F, Brusa C, Rossi F, Rolle E, Placentino V, Berardinelli A, Pagliardini V, Porta F, Spada M, Mongini T.
Eur J Paediatr Neurol 2018. 22(6),1103-1109.
Progression of Pompe disease was evaluated in 8 young patients.
From the results of the study, the authors suggest using MFM-20 in young patients with Pompe disease.
Keywords: Children; Cognitive evaluation; Emerging phenotype; Motor function; Outcome measures; Pompe disease
Articles in scientific journals
How to Best Measure Disease Progression in Adult Spinal Muscular Atrophy Patients: A Clinical and Neurophysiological Study
da Graça FF, Iwabe C, Nucci A, de Rezende TJR, França MC Jr.Muscle Nerve 2026 Feb 2. doi: 10.1002/mus.70169This study aimed to identify the most sensitive clinical, patient-reported, and neurophysiological measures to detect short-term disease progression in untreated...
Rasch analysis to evaluate the motor function measure for patients with facioscapulohumeral muscular dystrophy
Mul K, Horlings CGC, Faber CG, van Engelen BGM, Merkies ISJ. Int J Rehabil Res. 2021. 1;44(1):38-44. A Rasch analyses was performed on MFM data from 194 FSHD patients to assess clinimetric properties in this patient group.Rasch analysis revealed multiple limitations...
Assessment of the validity and reliability of the 32-item Motor Function Measure in individuals with Type 2 or non-ambulant Type 3 spinal muscular atrophy
Trundell D, Le Scouiller S, Le Goff L, Gorni K, Vuillerot C. PLoS One. 2020. 18;15(9):e0238786. This study sought to investigate the reliability, validity, and ability to detect change of MFM32 in subjects with Type 2 and non-ambulant Type 3 Spinal Muscular Atrophy...
Assessment of respiratory muscles and motor function in children with SMA treated by nusinersen
Gómez-García de la Banda M, Amaddeo A, Khirani S, Pruvost S, Barnerias C, Dabaj I, Bénézit A, Durigneux J, Carlier RY, Desguerre I, Quijano-Roy S, Fauroux B. Pediatr Pulmonol. 2021. 56(1):299-306. Respiratory muscles performance and lung function were evaluated in...
Association Between Health-Related Quality of Life and Motor Function in Ambulant and Nonambulant Duchenne Muscular Dystrophy Patients
Gocheva V, Schmidt S, Orsini AL, Hafner P, Schaedelin S, Rueedi N, Weber P, Fischer D.J Child Neurol. 2019. 34(14):873-885.Cross-sectional study assessing health-related quality of life (HRQOL) in ambulant and nonambulant patients with Duchenne muscular dystrophy, and...
Validity and Reliability of the 32-Item Motor Function Measure in 2- to 5-Year-Olds with Neuromuscular Disorders and 2- to 25-Year-Olds with Spinal Muscular Atrophy
Trundell D, Le Scouiller S, Gorni K, Seabrook T, Vuillerot C, SMA MFM Study Group.Neurol Ther. 2020. 9(2):575-584. Investigation of the validity and reliability of the MFM32 in individuals with neuromuscular disorders (NMD), including spinal muscular atrophy (SMA),...